How Cymbalta Is Believed to Work
Cymbalta is indicated for the treatment of major depressive disorder. The efficacy of Cymbalta was established in four short-term and one maintenance trial in adults.
Cymbalta is indicated for the treatment of generalized anxiety disorder (GAD). The efficacy of Cymbalta was established in three short-term and one maintenance trial in adults.
Cymbalta is indicated for the management of diabetic peripheral neuropathic pain and fibromyalgia.
Cymbalta is indicated for the management of chronic musculoskeletal pain due to chronic osteoarthritis pain and chronic low back pain.
Cymbalta is not a narcotic.
Although the exact way that Cymbalta works in people is unknown, it is believed to be related to an increase in the activity of serotonin and norepinephrine, which are two naturally occurring substances in the brain and spinal cord.
Cymbalta is in a class of medications called selective SNRIs (serotonin and norepinephrine reuptake inhibitors).
Learn about serotonin and norepinephrine, two naturally occurring substances in the brain and spinal cord.
You can also see Important Safety Information, including Boxed Warning about antidepressants and risk of suicide, Prescribing Information, and Medication Guide.