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Home > Depression > Information for Caregivers > Common Questions About Treatment

Common Questions About Treatment

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Starting treatment can be a huge relief for both the depressed person and his or her family and friends. Treatment can be either medication, therapy, or both. But treatment can raise a number of concerns for everyone involved.

How soon will my friend or family member start to feel better?
Getting better doesn't happen overnight. It happens gradually. With most antidepressants, it can take up to four to six weeks of consistent treatment to feel the full benefit of the medication. Of course, the timing can vary depending on the antidepressant and the individual. With some medications, many people may begin to see improvement of their symptoms of depression within one to four weeks.

Will there be any side effects to Cymbalta?
All medications have side effects, but everyone responds differently to medications. Talk to your physician about any concerns you may have about your medication. The three most commonly reported side effects of Cymbalta include:

  • Nausea
  • Dry mouth
  • Constipation

These side effects were reported during clinical trials of depression. For complete safety information, please read the full Safety Information.

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Will being on an antidepressant change my loved one's personality?
No. What medication will do is help lift the cloud that's preventing your loved one from functioning at his or her best. It won't change who that person is—although you may find that your loved one has a renewed sense of hope and is more active.

Who will be in charge of monitoring my friend or family member's progress?
If the person is taking an antidepressant, he or she should be checking in with a healthcare professional to assess how the medication is working and discuss any side effects. That may be the person's primary care physician, or it may be a specialist, such as a psychiatrist. In addition, your loved one may be undergoing psychotherapy with a different healthcare professional, such as a psychologist or licensed clinical social worker.

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What if the medication isn't working or my loved one doesn't take it as prescribed?
To feel the full benefits of an antidepressant, it must be taken as prescribed for an adequate length of time. Many people don't give their antidepressant medication enough time to do its job properly. Encourage your loved one to talk to the doctor before they stop taking the medication.

If the doctor does recommend taking your loved one off medication, he or she will probably advise decreasing the dose slowly. Some antidepressants can cause uncomfortable side effects if stopped abruptly, which is why he or she should not stop taking medication without talking to the doctor.

However, it is vital to first give the medication enough time to work. People are often tempted to stop taking their medication as soon as they start to feel better. Or they think they can take days off. But antidepressants aren't like aspirin—they shouldn't be taken sporadically. Studies suggest that treatment with antidepressants can reduce the risk that the depression will return. Treatment guidelines recommend continuing treatment for at least a further 6 months to minimize the risk of relapse. The National Institute of Mental Health (NIMH) suggests that some patients, such as those with chronic depression or those who have experienced multiple episodes of depression, may need to stay on antidepressant medication indefinitely.

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