Learn how Cymbalta can help treat or manage your symptoms. More

I have been prescribed Cymbalta for:

Depression Impact Tool

The Depression Impact Tool allows you to learn about depression and build a list of your symptoms, as well as rate how much those symptoms affect your life. Choose a number from 0 to 10, where 0 indicates that the symptom has no impact on your everyday life and 10 indicates that the symptom has the greatest impact on your everyday life. It is important to remember that this is not a "score," but a way to communicate how much you believe the symptom affects your everyday life.

When you finish, you'll be able to print out your symptoms and share this information with your doctor. Rate all that apply to you.

Cymbalta and depression

Treating depression with Cymbalta

Sadness throughout the day, nearly every day
Feeling sad is a natural part of life, but prolonged sadness can be a symptom associated with depression, especially if you find that your sadness interferes with everyday life.

Loss of interest in or enjoyment of your favorite activities
If you have lost interest in the things you once enjoyed, like going to the movies, hanging out with friends, or walking the dog, you may be experiencing one of the common symptoms of depression.

Feelings of worthlessness
Do you feel like you don't matter or that you don't deserve to be happy? Have you experienced these feelings for an extended period of time?

Excessive or inappropriate feelings of guilt
Having excessive feelings of guilt should raise a red flag. Are you constantly blaming yourself when things don't turn out well? You may have done nothing wrong, but maybe you feel like what you do is never right.

Thoughts of death or suicide
Thoughts of death or suicide are common in depression, and it's important to take these thoughts seriously. If you feel like giving up, call the National Suicide Prevention Helpline, 1-800-SUICIDE (1-800-784-2433).

Trouble making decisions
Having trouble making decisions? Do the little things frustrate you? Do some decisions seem too overwhelming or burdensome?

Fatigue or lack of energy
Feeling tired or fatigued nearly every day may be associated with depression. Do you drag yourself out of bed each morning? Do you feel like you have no energy to make dinner or do laundry?

Sleeping too much or too little
Sleeping too much or not enough may be a symptom of depression. Do you stay awake at night and feel sleepy during the day? Studies suggest that many with depression may have a variety of sleep problems.

Change in appetite or weight
A weight change of more than 5% (up or down) in a month when you haven't been trying to gain or lose weight may be a sign of depression.

Trouble concentrating
Has your performance at work gone down because you can't concentrate? Are you unable to focus on your daily tasks and projects? Is your mind always racing?

Feeling Slowed Down
Has your speech slowed? Do you feel like your thinking has slowed? Are your moving more slowly?

Restlessness
Are you easily agitated? Do you have trouble sitting still? Do you pace back and forth?



Cymbalta® (duloxetine HCl) is approved for the treatment of depression and generalized anxiety disorder, and for the management of diabetic peripheral neuropathic pain and fibromyalgia. What should I talk about with my healthcare provider? Patients on antidepressants and their families or caregivers should watch for new or worsening symptoms, unusual changes in behavior, thoughts of suicide, anxiety, agitation, panic attacks, difficulty sleeping, irritability, hostility, aggressiveness, impulsivity, restlessness, or extreme hyperactivity. Call your healthcare provider right away if you have thoughts of suicide or if any of these symptoms are severe or occur suddenly. Be especially observant within the first few months of antidepressant treatment or whenever there is a change in dose. You should also know that: Suicide is a known risk of depression and some other psychiatric disorders. Antidepressants may increase suicidal thoughts or behaviors in some children, adolescents, and young adults especially within the first few months of treatment or when changing the dose. No increased risk has been shown for adults over age 24, and risk decreased for those over age 65. All patients starting therapy should be monitored appropriately and observed closely for new or worsening depression symptoms, suicidal thoughts or behavior, or unusual changes in behavior. Cymbalta is not approved for use in patients under age 18. Who should NOT take Cymbalta? You should not take Cymbalta if: You have recently taken a type of antidepressant called a monoamine oxidase inhibitor (MAOI) You have uncontrolled narrow-angle glaucoma (an eye disease) You are taking Mellaril® (thioridazine) What other important information should I discuss with my healthcare provider? Before starting Cymbalta, tell your healthcare provider: about all of your medical conditions, including kidney problems, glaucoma, or diabetes about your alcohol use if you are taking nonprescription or prescription medicines, including those for migraine, to address a possible life-threatening condition if you are taking NSAID pain relievers, aspirin, or blood thinners. Use with Cymbalta may increase bleeding risk if you are pregnant, plan to become pregnant during therapy, or are breastfeeding an infant While taking Cymbalta, tell your healthcare provider: if you have itching, right upper belly pain, dark urine, yellow skin/eyes, or unexplained flu-like symptoms, which may be signs of liver problems. Severe liver problems, sometimes fatal, have been reported if you have high fever, confusion, and stiff muscles to address a possible life-threatening condition before stopping Cymbalta or changing your dose if you experience dizziness or fainting upon standing, especially when first starting Cymbalta or when increasing the dose. Your healthcare provider may periodically check your blood pressure while you are taking Cymbalta If you have any questions, talk to your healthcare provider before taking Cymbalta. What are the possible side effects of Cymbalta? The most common side effect of Cymbalta was nausea. For most people who had it, the nausea was mild to moderate. Other common side effects included dry mouth, sleepiness, constipation, decreased appetite, and increased sweating. This is not a complete list of side effects. Please read additional Safety Information and Boxed Warning for a complete list.
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