What Causes Depression?

Patient stories about depression

Hear patients and caregivers talk
about depression. Open Real Stories

There's no simple explanation as to why people experience depression. It's a complex disease that may develop for a variety of reasons. It can affect anyone at any age, regardless of gender, race, ethnicity, or income level.

Some people become depressed after a major life change—the death of a loved one, a divorce, the loss of a job, or a move. Even seemingly happy events, such as becoming a parent or getting married, can trigger depression. Or, even a smaller change can sometimes trigger depression. Some risk factors for depression include:

A family history of depression
Death or illness of a loved one
Stressful conflicts, such as fights with family members or disputes at work
Physical, sexual, or emotional abuse
Major life events, such as moving, graduating from college, changing jobs, getting married or divorced, becoming a new parent, or retiring
Financial difficulties

It is important to seek help if you think you are depressed.

Learn about symptoms of depression or get tips on talking to your doctor about depression.